| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6823877e88993ad7362c7b16945538b7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| filingDate |
2013-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffc47cf253cfefe34a8b0abb3054ef31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94907b40c63979ff80365dc4706ea4eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65dd97c1ddf5a2bb5b875a5136323af1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_054964df4c0ebab0140f1c6861a58a88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10c217f8a6815966ffbe485af5dc138a |
| publicationDate |
2014-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014046417-A1 |
| titleOfInvention |
Method for preparing mesenchymal stem cell aggregates |
| abstract |
Disclosed is a method for preparing mesenchymal stem cell aggregates, which comprises the steps of (1) culturing mesenchymal stem cells in a medium containing calcium in a concentration of from 2.1 to 3.8 mM and magnesium in a concentration of from 1.0 to 3.0 mM under a hypoxic condition with a 2 to 5% of oxygen concentration; and (2) forming aggregates by culturing the mesenchymal stem cells thus obtained in a medium containing serum replacement instead of fetal bovine serum. The mesenchymal stem cell aggregates prepared by the method above have a dense and rigid structure, improved immunological properties and excellent secretion of cytokines, and thus can be used as a cell therapeutic agent safely and effectively. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3299023-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018065092-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3305306-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107287157-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3041930-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018053618-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110227058-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108486035-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108486035-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114457010-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10150950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115851590-A |
| priorityDate |
2012-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |