Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6171684de68ce62ef3fbf1655618249 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 |
filingDate |
2013-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78a12f587d66d8d80242df684a15590c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af275497f473f28bb7098f55eb04cad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec9263ee7e374d2fb048d89fded0f427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf4c829eb9d017f85c4d093a0cebaa82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4c387f97bf157b4bf5a29ebd037e1a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5c41b309c3fd25f6b0b95df90b43ac4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcdb7562075179e1ab44c7c9bf1c9943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e7618cd55ee20097d42e5028edc3f75 |
publicationDate |
2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2014042392-A1 |
titleOfInvention |
Composition using metformin for preventing or treating immune diseases including lupus |
abstract |
The present invention relates to a composition for preventing or treating immune diseases through the suppression of B cell activity induced by metformin.nMore particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by the suppression or reduction of B cell activity which is a cause of disease. The present invention can be valuable in the use thereof for various autoimmune diseases as an immunosuppressant which can prevent or treat immune diseases by suppressing or reducing B cell activity and Th17 cell activity, which are causes of disease, or by promoting or increasing regulatory T cell activity. |
priorityDate |
2012-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |