| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73b46a19d9635f31a98d8919333159f4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2013-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29d6af218ac7f05b9147951f49bb4f1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14f7d985c08d150b52048ee9aee1c2d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1ec4fcf16c8f4b3417c43be67021021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f6c4823048071b3f2f9641338429a3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2c3921909336b21355bde25205fab71 |
| publicationDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014037460-A2 |
| titleOfInvention |
Immobilised cyclin-dependent kinase 4 fusion proteins and uses thereof |
| abstract |
The present invention concerns an in vitro assay for determining the activation status of endogenous CDK4 in eukaryotic cells, said assay comprising the steps of: providing eukaryotic cells maintained in a quiescent state, said eukaryotic cells comprising a cyclin D/CDK4 fusion protein, wherein the CDK4 part of the fusion protein is present in a hypophosphorylated form; inducing proliferation of said eukaryotic cells; isolating the cyclin D/CDK4 fusion protein from said eukaryotic cells; and measuring the activation status of said isolated cyclin D/CDK4 fusion protein, thereby determining the activation stats of endogenous CDK4 in said eukaryotic cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2583741-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2583741-A |
| priorityDate |
2012-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |