http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014031586-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_698e3cee5d881fd8df4bbe99c41394ac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 |
| filingDate | 2013-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a550fc6bd992de63eda3dbe3bb8a55be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb10e02a6015dad149b2615ca6bb8cc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82e50e3f31c382f8d906ad86d68a879e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2588015f4e21e543e52e5b1c5e024446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d36f1c270b344510266cd190c21c294 |
| publicationDate | 2014-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2014031586-A2 |
| titleOfInvention | Methods for treating cardiovascular diseases |
| abstract | The present invention is based in part on the discovery that an inhibitor of the 5-lipoxygenase pathway (for example, a 5-lipoxygenase inhibitor or a 5-lipoxygenaseactivating protein (FLAP) inhibitor) can preserve and improve cardiac function, mitigate cardiac dysfunction, as well as reduce epicardial adipose tissue and/or pericardial adipose tissue in a subject suffering from a cardiovascular disease. Accordingly, the present invention provides methods for mitigating cardiac dysfunction in a subject in need thereof by administering to the subject a composition comprising a 5-lipoxygenase inhibitor or a FLAP inhibitor. The present invention further provides methods for preserving and/or improving cardiac function in a subject in need thereof by administering to the subject a composition comprising a 5-lipoxygenase inhibitor or a FLAP inhibitor. In addition, the present invention provides methods for reducing epicardial adipose tissue and/or pericardial adipose tissue in a subject in need thereof by administering to the subject a composition comprising a 5-lipoxygenase inhibitor or a FLAP inhibitor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189830-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020144192-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105078957-A |
| priorityDate | 2012-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 341.