abstract |
A system and method that quantifies the concentration of an immunoactive analyte by detecting a chemically amplified change in density. This method, termed DeLISA for Density-Linked Immunosorbent Assay, but useful for any biomolecular recognition event, uses magnetic levitation (MagLev) io detect the changes in density. The present disclosure provides a quantitative measure of detecting binding events, does not require the use of electricity, and can be easily multiplexed to detect multiple analytes since several beads can be placed in single serum sample to detect, for example, HIV, Syphilis, Hepatitis C, and the like, simultaneously. |