| abstract |
[Problem] To provide a novel compound having EP 1 receptor antagonist activity. [Solution] A pyrazolopyridine derivative indicated by general formula (I) or a pharmacologically acceptable salt thereof was found to have powerful EP 1 receptor antagonist activity. The compound (I) or a pharmacologically acceptable salt thereof is effective as a therapeutic medication or preventative medication for lower urinary tract symptoms (LUTS), for example, and for overactive bladder syndromes (OABs), etc., in particular. In addition, same are highly useful in the treatment, prevention, or suppression of a variety of conditions involving EP 1 receptors, in addition to lower urinary tract symptoms (LUTS), (e.g., inflammatory conditions, painful conditions, osteoporosis, cancer, etc.). |