http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014016789-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c3e182c0c7bc69e566750a7c5d0bdda |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7a198eaecda96cae400a280c4d689e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ee8ed58044d9df7f40e2bd48f670319 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee4e18adc9edea0b6061a32415a7aa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c75d8ce91b2076fd6ef1e2d42703c8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2e90f7d01f272f304521d6fb82cd800 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7242db50ad752d9bf2454b872008eac |
publicationDate | 2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2014016789-A1 |
titleOfInvention | Pyrazolo[3,4-d]pyrimidin-4(5h)-one derivatives as pde9 inhibitors |
abstract | A compound of the general formula (I) wherein R 1 is selected from the group consisting of phenyl unsubstituted or substituted with 1 to 3 substituents selected from F, Cl, Br, I, CN, -O-C1-C3-alkyl, fluorinated -O-C1-C3-alkyl, -(CH 2 ) m OH and 5-membered heterocyclic group with 1 or 2 heteroatoms selected from N, O and S; and 6- or 10-membered heteroaryl with 1 to 3 heteroatoms selected from O, N and S; R 2 and R 3 independently of each other represent H atom or straight or branched C1-C3 alkyl; R 4 is selected from the group consisting of 4- to 6- membered cycloalkyl, wherein one of carbon atoms can be replaced by O atom, and which is unsubstituted or substituted with one or two halogen atoms,and straight or branched C1-C4 alkyl; Q represents a bond or C1-C3-alkylene, which can be optionally substituted by one to three C1-C3-alkyls; X is selected from the group consisting of O, NR 5 , and S(O) p ; R 5 represents H atom or C1-C3alkyl; m is 1, 2 or 3; p is 0, 1 or 2; and salts thereof, for use as a medicament, in particular for treating cognitive function disorders and neurodegenerative diseases. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669680-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3892622-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113166159-A |
priorityDate | 2012-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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