| abstract |
The invention relates to highly branched macromolecules referred to as dendrimers or dendrons, which have a carbosilane structure and are functionalised on the periphery thereof with anionic or cationic groups which give the macromolecule a negative or positive net charge, respectively. Said molecules were synthesised from a polyvalent nucleus, in particular a polyphenolic nucleus or a silicon atom nucleus, were obtained as spherical dendrimers, or else as dendritic wedges, having a point of growth known as the focal point. The functionalisation of the periphery of said dendrimers is carried out by thiol-ene or thiol-yne reaction between a thiol that contains the anionic or cationic group, or the corresponding precursor thereof, and a dendrimer functionalised with terminal olefins or alkynes. The invention further relates to the method for obtaining same and to the uses thereof in biomedicine. |