| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08b460d9b492971a6bd0b985c2a7f2d6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| filingDate |
2013-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19fb2ab68b39e2981d8c8887877618f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32d5b8107b98f2a37a0084bccc38e52e |
| publicationDate |
2014-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2014015137-A2 |
| titleOfInvention |
Compositions and methods for treating dysproliferative diseases |
| abstract |
Methods are provided for treating cancer and other dysproliferative diseases by administering to a subject in need there of a therapeutically effective amount of a synergistic composition comprising an HER2 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; and a CYP26 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; wherein said therapeutically effective amount suppresses the growth of dysproliferative cells in vivo. Compositions comprising a combination of an HER2 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; and a CYP26 inhibitor a pharmaceutically acceptable salt or prodrug thereof are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434234-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017524010-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10556893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020171146-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016025424-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015301891-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11459319-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10851095-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107074841-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107074841-A |
| priorityDate |
2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |