Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd15d8ebb22202b5cfe2b109cd922c5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 |
filingDate |
2013-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0680f6f15ff0c5c9e3d43bce86ca7510 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52c064fa5d1ca07efe5167597ea6c208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3be4872023b7f552d88292701aae3722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87c1fbf9d253e8ba55480be0a89f8a2a |
publicationDate |
2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2013191509-A1 |
titleOfInvention |
Pharmaceutical composition for preventing and treating parkinson's disease, containing n-terminal truncated ubiquitin c-terminal hydrolase-l1 (nt-uch-l1) as active ingredient |
abstract |
The present invention relates to a pharmaceutical composition for preventing and treating Parkinson's disease, containing N-terminal truncated ubiquitin C-terminal hydrolase-L1 (NT-UCH-L1) as an active ingredient. Specifically, it is ascertained that NT-UCH-L1 in which 11 amino acids are removed from the N-terminal of UCH-L1 is placed in mitochondria, thereby playing an important role in the regulation of stress inducing active oxygen species and mitochondrial damage, and thus NT-UCH-L1 can be used as an active ingredient of a composition for preventing and treating Parkinson's disease. |
priorityDate |
2012-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |