| abstract |
Provided is a composition for improving and/or treating central nervous system degenerative disease associated with learning and memory impairment. A composition for improving and/or treating central nervous system degenerative disease, containing as an active ingredient at least one compound selected from: compound (S4) (sinensetin) in which R 1 , R 2 , R 3 , and R 4 in general formula (I) are methoxy groups and R 5 is H; compound (S3) (6-demethoxytangeretin) in which R 2 , R 4 , and R 5 are methoxy groups and R 1 and R 3 are H; and compound (S2) (6-demethoxynobiletin) in which R 1 , R 2 , R 4 , and R 5 are methoxy groups and R 3 is H. |