Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98374f168c43d1b57d81c37017bfcef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2cd0454dd1dc095d90cd25a293cd1fa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-00 |
filingDate |
2013-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a696d7a26299e3b24842f74f290f99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_554ddbbd2c17d5911273b45873eab2cc |
publicationDate |
2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2013188600-A1 |
titleOfInvention |
Copy number aberration driven endocrine response gene signature |
abstract |
Disclosed are methods of predicting the likelihood of long-term survival without recurrence of breast cancer for a subject having estrogen receptor-positive (ER+) breast cancer treated with adjuvant endocrine monotherapy. In various embodiments, these methods comprise performing a gene expression profile of a breast tissue sample of substantially all of the genes of the "CADER set" described herein; calculating a risk score using a regression model; and applying a double median cutoff classification to assign the subject to a sensitive, indeterminate or resistant group, wherein assignment to a sensitive group predicts longer relapse-free survival compared to the median relapse-free survival of ER+ breast cancer patients treated with adjuvant endocrine monotherapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108090328-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113506309-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108090328-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017096457-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10607717-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2016368696-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11574704-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109072481-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10851427-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019051266-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11505832-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11566292-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2541405-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109072481-B |
priorityDate |
2012-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |