| abstract |
The present invention relates to linker molecules that readily conjugate cellular recognition ligand at one end and drug payload at the other, and are useful in treating or preventing cancer, an autoimmune disease, an inflammatory condition, a central nervous system disorder or an infection. The linker inker molecules of the invention are represented by Formula (I), (II) and (II)I; Linker- Drug compounds represented by Formula (IV), (V) and (VI); and Ligand-Linker-Drug conjugates represented by Formula (VII), (VIII) and (IX): |