| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcce39a20bef16c3f04497659caba40f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 |
| filingDate |
2013-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_224fab14f951f8dcf0d022e4c0149fed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_053e172af0d842f4400fbf4e81cee6f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9752516d3b1eca0831abc7edafc7d8a0 |
| publicationDate |
2013-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013177498-A1 |
| titleOfInvention |
Agonists of neuronal nicotinic acetylcholine receptor a7 subtype for use in the treatment of cognitive symptoms of schizophrenia |
| abstract |
The present invention relates to pharmaceutical compositions for use in the treatment of cognitive symptoms of schizophrenia or a related schizophrenia spectrum psychotic disorder, comprising administering a therapeutically effective amount of a selective agonist of neuronal nicotinic acetylcholine receptor α7 subtype and a pharmaceutically acceptable excipient to a nonsmoker patient in need of treatment. The selective agonist of neuronal nicotinic acetylcholine receptor α7 subtype is preferably (4s)-4-(5-phenyl-1,3,4-thiadiazol-2-yloxy)-I- azatricyclo[3.3.1.1 3,7 ]decane, (N-[(3R)-l-azabicyclo[2.2.2]oct-3-yl]-7-chloro-l- benzothiophene-2-carboxamide) or (N-[2-(pyridin-3-ylmethyl)-l-azabicyclo[2.2.2]oct-3-yl]- l-benzofuran-2-carboxamide) or a salt thereof. |
| priorityDate |
2012-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |