http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013173688-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_520beda42d8211f2877dce94e8a9c98c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23aad7933d7c54dddcb9d6cea4f85133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dfe43ab35f9296d09ee11365e004609 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1384 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 |
| filingDate | 2013-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a5dc8171f4012b17a126a76963183a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec1c2db7d90b5117e6f3289097f5df41 |
| publicationDate | 2013-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2013173688-A1 |
| titleOfInvention | A method of making tissue engineered blood vessels and generating capillary networks, articles, and methods of use thereof |
| abstract | A method of making a tissue engineered blood vessel (TEBV) having a lumen or generating capillary networks comprising obtaining fat or bone marrow from an individual, isolating human stem cells fat or bone marrow, treating the stem cells with endotheliogenic medium and an agent selected from the group consisting of sphingosine-1-phosphate (S1P); 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol (FTY-720P); 2-amino-2-(1,2,12-trihydroxy-4-octadecenyl)-1,3-propanediol; 6-Eicosene-1,3,4-triol, 2-amino-2-(hydroxymethyl)-1,3-propanediol; 1,3,4,14-Eicosanetetrol, 2-amino-2-(hydroxymethyl)-1,3-propanediol; and 1,3,4-Eicosanetriol, 2-amino-2-(hydroxymethyl)-1,3-propanediol, and either coating the lumen with the treated stem cells or injecting the treated stem cells into ischemic tissues of the individual. The novel, resultant regeneration of vascular structures can fully integrate into pre-existing vascular segments and in some cases are indistinguishable from the individual's native blood vessels. The TEBV can also be made by annealing S1P and heparin to the lumen. |
| priorityDate | 2012-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.