| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e9d56972b7dc22e3dfb093ae22d533 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-161
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-40 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-508
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
2012-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a00fda0acfa9c6ffb422c819adec8ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b5cdb9250a713b40335545c2129b74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36b242020302b02e5deaf402a9f17987 |
| publicationDate |
2013-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013162482-A1 |
| titleOfInvention |
A grid containing systematically distributed micro- nanopillar coated fields to control cell adhesion |
| abstract |
The invention provides a method where a test platform consisting of systematically varied micro and nanopillar based topographies is used to determine cell specific dimensions to prevent or promote adhesion and/or alignment of cells, microorganisms. Also the wetting by liquids can be promoted or prevented without the need for chemical cues. Furthermore, the preferences (responses to surfaces) could be modified by additional chemical treatments. The test platform design is based on nano-micropillar covered fields where the distance between the pillars (ca. 900 nanometers and 1.3 micrometers tall, 200 nanometers wide) and are varied from 1 to 10 micrometers creating a grid of pillars. These fields are separated by pattern-free regions. In addition to preventing or promoting adhesion, the test platform appears to trigger mammalian cells to align. The cell adhesion property of the fields could be modified by coating the surface with biopolymers or by changing the stiffness of the material of the surface. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610621-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104928180-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278941-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019090478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021161291-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11785943-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11116877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2918675-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9962701-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11717821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018152445-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10814046-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017117108-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113368126-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10736997-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018182556-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697141-B2 |
| priorityDate |
2012-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |