abstract |
Methods of inhibiting lymphangiogenesis and/or angiogenesis in a subject are provided. In one aspect, for example, a method of inhibiting angiogenesis in a subject can include binding an antisense morpholino to an mRNA splicing site of VEGFRl selected from exonl3_intronl3 junction, intronl3_exonl4 junction, or a combination thereof. In another aspect, the morpholino includes a member selected from VEGFRl_MOel3, VEGFRl_MOil3, or a combination thereof. |