| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00a421ab71bd49a451d0a49d23a082c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8528ff66470c896b6da8ed059464e31f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4ef1740fd2dd198950e06fecce1452 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01044 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-85 |
| filingDate |
2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80a74ba513c84a46eeb5d53bdb44e762
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf229a4c6df47b3ffb704631e64db752
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ff9eb4b090f0a4825f250155206bcab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29ea7b8e790d0a14f092fa9032344d5c |
| publicationDate |
2015-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013158749-A3 |
| titleOfInvention |
Engineered microorganisms with improved growth properties |
| abstract |
The present application relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial pyruvate-derived metabolites, e.g., isobutanol. In some embodiments, the recombinant yeast microorganisms may be is engineered to comprise reduced PDC activity. In additional embodiments, the recombinant yeast microorganisms may be engineered to (a): comprise at least one first modification which results in improved growth in the absence of C2-supplementation as compared to the corresponding recombinant yeast microorganism without said first modification; and/or (b) comprise at least one second modification which results in improved tolerance to glucose as compared to the corresponding recombinant yeast microorganism without said second modification. |
| priorityDate |
2012-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |