| abstract |
Disclosed in the present invention is a 3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs; the 3-cyanoanilinoalkylarylpiperazine derivative disclosed by the present invention has very useful pharmaceutical properties and good tolerance, especially the use as novel analgesics, novel antidepressants, and novel analgesic and antidepressive drugs. This class of compounds are central analgesics regulating 5-hydroxytryptamine, and also are novel antidepressants regulating 5-hydroxytryptamine. This class of compounds also has less toxic and side effects and a higher safety range. The 3-cyanoanilinoalkylarylpiperazine derivative is a compound shown as formula （III） or free base or salt thereof. |