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filingDate 2013-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013150407-A1
titleOfInvention Mr imaging using apt contrast enhancement and sampling at multiple echo times
abstract The invention relates to a method of CEST or APT MR imaging of at least a portion of a body (10) placed in a main magnetic field B 0 within the examination volume of a MR device. The method of the invention comprises the following steps: • a) subjecting the portion of the body (10) to a saturation RF pulse at a saturation frequency offset; • b) subjecting the portion of the body (10) to an imaging sequence comprising at least one excitation/refocussing RF pulse and switched magnetic field gradients, whereby MR signals are acquired from the portion of the body (10) as spin echo signals; • c) repeating steps a) and b) two or more times, wherein the saturation frequency offset and/or a echo time shift in the imaging sequence are varied, such that a different combination of saturation frequency offset and echo time shift is applied in two or more of the repetitions; • d) reconstructing a MR image and/or B 0 field homogeneity corrected APT/CEST images from the acquired MR signals. Moreover, the invention relates to a MR device (1) for carrying out the method of the invention and to a computer program to be run on a MR device.
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