http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013149904-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00a421ab71bd49a451d0a49d23a082c7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d104af7bf3b3460fd450b6f00cd7523a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5059ffc4a461b39342e768efee3f859 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f2d8d86df7d52bf5a3fd8f91076636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c50f1de78eb7276ba9119c47a7e90b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6abc22347cdb5e48f5d0cb23bdf6a26 |
| publicationDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2013149904-A1 |
| titleOfInvention | Marker gene based diagnosis, staging and prognosis of prostate cancer |
| abstract | This invention relates generally to a method of diagnosis and prognosis, in particular staging and/or typing and/or predicting outcome, for distinguishing between a benign prostate hyperplasia and a prostate cancer and between an hormone sensitive and an hormone refractory prostate cancer condition and specifically to identification of differentially methylated CpG islands in the regulatory regions surrounding the transcriptional start site of at least one marker gene of the present invention as a diagnostic and/or prognostic indicator of prostate cancer (PrCa) and for distinguishing androgen-refractory from androgen sensitive prostate cancer. The marker genes of the present invention comprise PITX2, and HOXD3. This invention relates more specifically to the detection of hypermethylation of PITX2, and HOXD3. This invention further relates to the prediction, prognosis or diagnosis of prostate cancer, including metastasis, more particularly in patients with prostate cancer. Marker genes have been identified of which promoter regions containing differentially methylated regions, compared to a reference sample, which are indicative for the prediction or prognosis of prostate cancer. |
| priorityDate | 2012-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.