| abstract |
The present invention can insert a therapeutic gene into both of vectors of a vector system in which the MuLV-Gag gene, the MuLV-Pol gene, and the GaLV-Env gene are divided into two vectors so as to be expressed, and thus it is possible to insert various foreign genes for therapy so as to safely and effectively transfer the same to a target cell tissue region of abnormal proliferation without a restriction on the size of the gene to be inserted. Therefore, it is possible to use: a composition, which contains a retrovirus produced by transfecting cell lines with the vector system, for transferring a gene targeting a cell of abnormal proliferation which abnormally divides; and a composition for preventing or treating diseases causing a cell of abnormal proliferation, such as cancer. |