| abstract |
The present invention relates to the method of synthesis of core-shell nano medicine serving as a novel platform for the encapsulation of multiple therapeutic molecules enabling combinatorial therapy against diseases including cancer, inflammatory and auto-immune diseases and its associated manifestations. The core-shell nano-construct comprises of a biodegradable and biocompatible polymer as the core and another polymer or protein as the shell, aiding following constructs (i) polymer core-polymer shell and (ii) polymer core-protein shell. The core-shell nano medicine is developed in a manner to encapsulate at least one anti-cancer agent each in both the core and the shell |