abstract |
The disclosure provides reagents, methods, and kits, for treating or preventing cancers derived from each of the germ layers (endoderm, mesoderm, ectoderm, neural crest). The reagent encompasses interferon-gamma (IFN-gamma) responsive cancer cells, where the cells are autophagic and non apoptotic cancer cells, and where the cells express MHC Class II. In another aspect, the reagent encompassed dendritic cells loaded with the IFN gamma responsive, non apoptotic, MHC Class II-expressing cancer cells. |