http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013112380-A3

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filingDate 2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5deb493c0eecfc94300e1514300377d7
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publicationDate 2013-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013112380-A3
titleOfInvention Bio-selective surface textures
abstract Bio-selective textured surfaces are described which mediate foreign body response, bacterial adhesion, and tissue adhesion on devices implanted in a mammalian body. Hierarchical levels of texture, some capable of establishing a Wenzel state others a Cassie state, are employed to interface with living structures, either to promote or discourage a particular biological response/interaction. Since a gaseous state is traditionally required to establish a Cassie or Wenzel state, and gases do not remain long in living tissue, described are tissue/device interactions analogous to the above states with the component normally represented by a gas replaced by a bodily constituent, wherein separation of tissue constituents develops and a desired interaction state evolves.
priorityDate 2012-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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