| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/E06B3-5842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/E06B3-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/E06B3-5828 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-258 |
| filingDate |
2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ca6779b806761e09200d70764fc0c08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_495d200687b4833bc89640a0d3ce757b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6d204e1e1b624d855c641aa83fd2617 |
| publicationDate |
2013-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013111969-A1 |
| titleOfInvention |
Composition containing tanshinone as active ingredient, for increasing differentiation or activity of natural killer cells |
| abstract |
The present invention relates to a composition containing tanshinone as an active ingredient, for increasing a differentiation or activity of natural killer (NK) cells. More particularly, the present invention relates to a composition in which cryptotanshinone or tanshinone IIA induces and promotes a differentiation of NK cells and increases an expression of ID2 which is a gene relating to an NK cell differentiation in hematopoietic stem cells. The cryptotanshinone or tanshinone IIA has cytotoxicity to YAC-1, which is a cancer cell, and also increases generation of IFN-γ, thus increasing the activity of NK cells. Therefore, the cryptotanshinone or tanshinone IIA can be effectively used as an active ingredient for a composition for increasing a differentiation or activity of NK cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109864991-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3925605-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109864991-A |
| priorityDate |
2012-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |