abstract |
The present disclosure provides facially arnphiphilic antimicrobial oligomers, pharmaceutically acceptable salts thereof, or a pharmaceutical composition thereof, useful for killing or inhibiting the growth of a Candida or Aspergillus species, as well as preventing or treating a mammal having oral or disseminated candidiasis or an aspergillus infection. The method(s) employed comprise(s) contacting the Candida or Aspergillus species with or administering to the mammal in need thereof an effective amount of such an antimicrobial oligomer, pharmaceutically acceptable salts thereof, or a pharmaceutical composition thereof. |