| abstract |
A compound of the structural formula I, a pharmaceutically acceptable salt, prodrug or derivative thereof, characterized in that R 1 is selected from H, a linear or branched (C1-C5) alkyl group and a COR 4 group; R 2 is selected from H, a linear or branched (C1-C5) alkyl group and a COR 5 group; R 3 is selected from H, a linear or branched (C1-C5) alkyl group, a linear or branched (C1-C5)- O-alkyl group, a cycloalkyl of (C5-C6) carbon atoms, an aryl group, and an aryl (C1-C5) alkyl group wherein the aryl group can be an unsubstituted aryl or an aryl substituted with one or more R 6 groups and an NHCOR 5 group, or the R 2 and R 3 groups together with N may form a substituted or unsubstituted piperidine, morpholine or piperazine group; R 4 is selected from H and a (C1-C5) alkyl group; R 5 is selected from an unsubstituted aryl group or an aryl group substituted with one or more R 6 , linear or branched (C1-C5) alkyl or pyridyne groups and a pyridine group; R 6 is selected from (C1-C5) alkyl groups, halogen and nitro, provided that R 1 , R 2 and R 3 are not H atoms at the same time. The compounds present antibacterial activity. Process for their preparation and pharmaceutical compositions comprising them are also disclosed. |