Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b2df0794da261663733565217ef801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85537cf0a4c5e7d7362a2765fbfa5b52 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate |
2013-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82ecfb6f4a9b1856914e982300df70f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af1c11c1c848997b86edd17fc5b1fc92 |
publicationDate |
2013-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2013103693-A1 |
titleOfInvention |
Nicked polynucleotide complexes for multivalent rna interference |
abstract |
The present invention includes multivalent nucleic acid complexes of nucleic acid molecules having two or more target-specific regions, in which the target-specific regions are complementary to a single target gene at more than one distinct nucleotide site, and/or in which the target regions are complementary to more than one target gene or target sequence. One oligonucleotide strand of the complex is nicked and thereby inactivated. Also included are methods of using the complexes for treatment of a variety of diseases and infections. |
priorityDate |
2012-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |