http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013101983-A3

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filingDate 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_902d9bdf5b8189345b41720e0b618cf5
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publicationDate 2013-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013101983-A3
titleOfInvention Targeted self-assembly 0f functionalized carbon nanotubes on tumors
abstract Provided herein are methods for delivering a molecule in situ to a cell and for treating a cancer via the in situ delivery. The methods comprise contacting or administering to the cell, as two separate components, a morpholino oligonucleotide comprising a targeting moiety followed by a single wall nanotube construct comprising second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct. Upon self-assembly of a single wall nanotube complex via hybridization of the first morpholino and second complementary morpholino oligonucleotides at the cell, the payload molecule is delivered. Also provided is the two component self-assembly single wall nanotube system and the single wall nanotube construct comprising the second component.
priorityDate 2011-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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