http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013100811-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d56b8b8ba8eeeabd70ae2280a6681c5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J53-002 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J53-00 |
filingDate | 2012-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73f8192b671056a81fef7105d2098b28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a0e6a301a7661210cf40c6cc1fe01f |
publicationDate | 2013-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2013100811-A1 |
titleOfInvention | PROCESS FOR OBTAINING 16α,17α-CYCLOHEXANO-5α,6α-EPOXYPREGN-3β-OL-20-ONE ACETATE |
abstract | The invention relates to the chemistry of natural and physiologically active substances and especially, to a process for obtaining an intermediate product in the synthesis of steroid hormones of the pregnane series. The process for obtaining 16α,17α-cyclohexano-5α,6α-epoxypregn-3β-ol-20-one acetate comprises treatment of 16α,17α-cyclohexanopregn-5-en-3β-ol-20-one acetate with an organic peracid in the medium of a polar organic solvent, its particular characteristic is that p- carbomethoxyperbenzoic acid is used as the organic peracid, and the process is carried out at the temperature of 25 - 30°C and at the molar ratio of 16α,17α-cyclohexanopregn-5-en-3β-ol- 20-one acetate : p-carbomethoxyperbenzoic acid 1 : 1.1 - 1.5. The technical result is the security and simplifying of the proposed process and the improved specificity of the process for providing generation of a a-isomer of the desired product; the process can be used in the manufacture of an intermediate product for the synthesis of. steroid hormones of the pregnane series, which represent valuable hormonal products used in medicine. |
priorityDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.