http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013091040-A2

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filingDate 2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013091040-A2
titleOfInvention Brucella ovis attenuated strain, vaccine composition and use
abstract The present invention describes an attenuated strain of Brucella ovis characterised in that it comprises a mutation of the gene that codes for the ABC-transporter (TMS3), and the use thereof as a live vaccine against brucellosis. More specifically, the present invention relates to the construction by directed mutagenesis of a mutant Brucella ovis strain (TMS3), by deletion of two open reading frames (ORF), BOVA0500 and BOVA0501 (GenBank), which code for proteins that form an ABC-transporter system.
priorityDate 2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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