http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013084208-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f218ced6ba06e24bfaa38739487aa2d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 |
| filingDate | 2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae29f84199c8cc549a41c99b9cef3498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99f15c1902cf4578fab51da4d56e0efa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb169b037e2f4917a862819832543ecb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f94074365b1592e17e5cf4c260927aef |
| publicationDate | 2013-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2013084208-A2 |
| titleOfInvention | Liposomes and method for producing the same |
| abstract | The present invention describes the use of conjugated peptide sequences enclosed in liposome membranes. Conjugation can be with a folic acid or an antibody of the folic acid receptor, which is coupled to the N-terminal of the peptide. The presence of these conjugated peptides in liposome formulations allows therapeutic agents and/or imaging agents to be specifically targetted to and subsequently released in cells with expression of folic acid receptors. The thus developed method allies the capacity of liposomes to transport and release drugs with the specific expression of receptors at the surface of cell membranes, allowing transmembrane transport mediated by specific liposomes. It thus can transport both hydrophobic and hydrophilic therapeutic and/or imaging agents inside the liposome. The therapeutic agents can be pharmacological compounds - active principles - or small interfering RNAs (siRNAs) specific to defined target genes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110548152-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020225769-A1 |
| priorityDate | 2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.