| abstract |
The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-8 antagonist may be, e.g., an antibody that spectficaiiy binds SL-6R, The 11-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist. |