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filingDate 2012-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b34b4f45eccec872bf497a1640832e1
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publicationDate 2013-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013059264-A1
titleOfInvention Embryonic stem cell models
abstract An embryonic stem cell model includes a first promoter-reporter system including survivin promoter and a second promoter-reporter system including a constitutive promoter. The change in the ratio of the expression of the first system to the expression of the second system is used to predict embryotoxicity. In particular, the first promoter- reporter system is used to predict embryotoxicity and the second promoter-reporter system is used to eliminate false positives caused by cytotoxicity.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021015611-A1
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