| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a35daa28b7044a7120e7f8eab9a07287 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate |
2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89840f17ef0dd2d3d1223f8f4dec71ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_354a285988322a5934e13d7a9aa088ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0497417f4a85c4893bc8cc48b8bb7c34 |
| publicationDate |
2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013054846-A1 |
| titleOfInvention |
Mutagenicity test method using mammalian cells |
| abstract |
The purpose of the invention is to provide a test method capable of accurately, easily, and in a short time confirming mutagenicity for mammals, including humans. To solve this problem, the invention provides a mutagenicity test method including (1) a step for culturing, for a predetermined period of time in the presence of the test substance, a transformant of a mammalian cell carrying a recombinant vector containing a p53 binding sequence, minimal promoter capable of functioning in a mammalian cell, and a reporter gene linked by this minimal promoter so as to be expressable and (2) a step for determining whether or not the test substance affects the expression level of the reporter gene in the transformant by comparing the expression level of the reporter gene in the transformant cultured in step (1) and the expression level of the reporter gene in a transformant not brought into contact with the test substance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10765094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015223107-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016017039-A1 |
| priorityDate |
2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |