http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013045500-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2858411320fb0a2e0a846742666185f9 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2012-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08275f852c32d18097f8a69625cf2a79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f43ceca635411c4f9a001b5cbba6dc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9710eb46a652734398a2894343db202c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f000ac9b002afabf118b0259a8266f53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83bce6d5ead4fcc66bd6394734a685db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c5fc43e3b02084f5dca20ace6b2a9a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0d8af2a951120f17b9134d6c66bfb99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11fd329661fd32b9e97daa910f3feeca |
publicationDate | 2013-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2013045500-A1 |
titleOfInvention | Method for determining a predictive function for discriminating patients according to their disease activity status |
abstract | The invention relates to a method for determining a predictive function for discriminating patients according to their disease activity status, comprising steps of: a -measuring values of biological markers for each patient of a first group of patients having a first known disease activity status, and for each patient of a second group of patients having a second known disease activity status, the measured values forming a dataset b –analyzing the dataset for identifying biological markers which are differentially expressed between the first group of patients and the second group of patients, c -among the biological markers identified at step b, determining correlated markers as markers which are correlated with other markers above a predetermined significance level, d –removing from the dataset, values measured for a biological marker identified as correlated marker, e -analyzing the dataset obtained at step d for determining a predictive function that predicts a disease activity status of a patient as a combination of values of biological markers, f -evaluating an accuracy index associated with the predictive function determined at step e, g –repeating steps d to f by selectively removing from the dataset, values measured for one or several biological marker(s) identified as correlated marker(s), so as to gradually decrease the number of biological markers in the combination of value until the accuracy index reaches an expected level. |
priorityDate | 2011-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 333.