| abstract |
Disclosed is a method of obtaining a silkworm gland-derived hydrolysate, which includes 1) preparing a silkworm, 2) lyophilizing the silkworm to separate glands, and dissolving the separated glands in water thus preparing a first solution, 3) centrifuging the first solution, thus recovering a supernatant, 4) adding an alkali to the supernatant, and hydrolyzing the supernatant, thus preparing a second solution, 5) adding an acid to the second solution so that the second solution is neutralized, thus preparing a neutralized solution, 6) desalting the neutralized solution, thus obtaining a hydrolysate, and 7) lyophilizing the hydrolysate, and which enables the production of the silkworm gland-derived hydrolysate using extraction at room temperature without the use of a harmful solvent, and exhibits superior cell proliferation effects. |