| abstract |
The present invention provides: a measurement method and a measurement reagent both improved in accuracy and a method for improving measurement accuracy, all of which are used in the measurement of periostin contained in a sample; and a method for detecting pulmonary fibrosis or interstitial pneumonia, which is improved in accuracy.nAn antibody according to the present invention can bind to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region and an R3 region of periostin or a decomposition product thereof.nAll of a method and a reagent both for measuring periostin and a method for improving the accuracy of the measurement of periostin according to the present invention are characterized in that at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region and an R3 region of periostin is detected.nA method for detecting pulmonary fibrosis or interstitial pneumonia according to the present invention comprises: a) a step of measuring the amount or concentration of periostin in a sample from a subject, wherein at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region and an R3 region of periostin is detected; and b) a step of comparing the amount or concentration of periostin in the sample from the subject with that in a sample from a living organism which is not affected by either pulmonary fibrosis or interstitial pneumonia. |