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publicationDate 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013028573-A1
titleOfInvention Gradient array dielectrophoresis separation (grads) with concomitant light therapy
abstract A method and device in which a heterogeneous population of cells or particles is introduced into a series of chambers with successively increasing dielectrophoresis fields produced by planar microelectrode arrays and thus separated by charge and size. A clear or translucent third electrode overlying the planar array defines the ceiling of the flow chamber and allows the simultaneous introduction of light therapy to cells while they are being separated. Flanking planar electrodes to the capture electrodes may be utilized for repulsive dielectrophoresis purposes in order to confine and keep separate entrapped cells during the final collection and elution phase. The entire process may be monitored electronically by impedance testing or visually by microscopy in-situ and real-time without disrupting the separation process.
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