Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ffd3aff0c3d36e1e47a09eaacd3a356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93529b169af9d1b0213bae3ee01dafed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62226ce6c115a2196837bd604bcb5358 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98d0ac8a38ad28fac92ab64bb50edd5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04070154c719cd78d182afa9ab0d9092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0b8352ef479c07ec6e1c9dd2362ba53 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0491 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2012-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e73358f303299d72226c8164492ac94f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abb09ca6be01270ebcb259d93759a269 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6bf1457b815970836092ad86c3909a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d7d874a76526cd180d58db030d82048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d945d1e53f1d5ef846cfd98f3961ec28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0a4f9cb12bfbc124d657cffc658a45e |
publicationDate |
2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2013022838-A1 |
titleOfInvention |
Non-immunogenic positron emission tomography reporter gene systems |
abstract |
Embodiments of the invention include a PET/SPECT reporter gene system that uses enhanced non-immunogenic versions of a human mitochondrial thymidine kinase 2 expressed in cytoplasm to preferentially trap novel PET/SPECT radiolabeled L and D-enantiomer analogs of the natural substrate thymidine. Such highly sensitive, non-immunogenic reporter genes function in combination with a set of novel, radiolabeled probes in whole body molecular imaging applications using positron emission tomography (PET) or single photon emission computed tomography (SPECT). |
priorityDate |
2011-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |