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publicationDate 2013-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2013022238-A3
titleOfInvention Tricyclic glycosylated derivative compound, a production method therefor, and an immunosuppressant pharmaceutical composition comprising a tacrolimus glycosylation derivative
abstract The present invention relates to a technique for producing tricyclic compound derivatives of novel structure by attaching a sugar to a tricyclic compound structure and relates to a glycosylation derivative synthesised by means of the technique; the immunosuppressant function being retained, and water-solubility being improved by a maximum of at least 10,000 times. Also, the present invention relates to a pharmaceutical composition for suppressing immune diseases including allergic conjunctivitis and xerophthalmia; and comprises a tacrolimus glycosylation derivative as an active ingredient.
priorityDate 2011-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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