| abstract |
The invention deals with the way of utilization of micronized, nanonized and/or surface-modified alaptide, which affects penetration of other pharmaceutically active compounds through the skin as a pharmaceutical adjuvant (excipient). These pharmaceutical compositions composed of alaptide as the excipient, pharmaceutical active ingredients (non-steroidal anti-inflammatory drugs and/or antipyretics/non-opiate analgesics and/or glucocorticoids and/or antimicrobial chemotherapeutics, i.e. antibacterials, antimycotics, antivirotics) and other pharmaceutical excipients can be used for preparation of drug formulations, which can influence the drug level in the body in time and can be used for both local and systemic administration. |