abstract |
Provided is novel 4-(3-heteroarylarylamino)quinazoline and 1-(3-heteroarylarylamino)isoquinoline of formula I, wherein ring C, A, R, and R 2 -R 10 are defined in the text. The compound of formula I is a Hedgehog pathway inhibitor.Therefore, the compound of the invention can be used for treating diseases resulting from abnormal Hedgehog activity, such as cancer. |