| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95dd6e29ba7fe73e4c1efb6b376c87a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c05bcf6c5582dc4bab3d7f21c3bf23fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b38c427a1bb0df6a9edf5484bea5d29b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15335e62cf1791d1118f52efe5bbbbc3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-4836 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 |
| filingDate |
2012-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ca6c615b8507fcf46a5e68a7351349f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8de0afec70a7bfd938b3d222bf0894d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcf55c0a3a504050f47c3ca1b7feb2ff |
| publicationDate |
2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013012498-A1 |
| titleOfInvention |
Electric cell- substrate impedance sensing (ecis) of biological samples in shear stress flow |
| abstract |
A system for characterizing the response of cells (201) to a condition, such as exposure to a pharmaceutical or other compound, includes a container (141) and an electrode array (101). The system is particularly suitable for performing electric cell-substrate impedance sensing (ECIS).The electrode array has a substrate (109) supporting a plurality of contact pads (105), a plurality of electrodes (103), and a plurality of electrical conductors (107) connecting the electrodes to corresponding ones of the contact pads. One or more electrically insulating materials (109, 115) covers the electrical conductors and has one or more openings (121) on the electrodes so the electrodes are not insulated by the insulating materials at the openings. The electrodes are positioned inside the container (141) and the contact pads are positioned outside the container. Cells (201) in the container can be exposed to hemodynamic shear forces by rotating a body (181) extending into a culture medium (191) in the container. Electrical impedance measurements between the electrodes can be used to assess the response of cells after exposure to the condition. A porous membrane (193) can be added to the container for allowing co-culture of cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102016224865-B3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11061016-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104569068-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10837957-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10514374-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10895546-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020134478-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018045714-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102016224865-B8
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7232078-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3933026-A4 |
| priorityDate |
2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |