abstract |
The present disclosure provides methods for assessing (e.g., measuring, analyzing, detecting, determining, evaluating, and/or estimating) the secondary structure of Glatiramer Acetate (GA) and, in some instances polymeric precursors of GA. The methods entail assessing the fraction of a sample of GA that is in alpha-helical conformation and/or assessing the fraction of a sample of GA that is in random coil conformation. |