| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f95f2ebec3bd110e4a0ef670f2d0c52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95652ab725448e8e7b6fa0ca9ebfacca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2766ab8cb1ef6f54a87633c72426861c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a5b8fa1cdf0fcf8681ae6958c3e3667 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-571 |
| filingDate |
2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfdb181dc60d8110bd2aa11dbc9434c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b69cb274ac6a87adf0899d49f2534289
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed559d394fff0a89c33f196c5eb92b2e |
| publicationDate |
2013-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013009739-A2 |
| titleOfInvention |
Soluble treponema pallidum protein tp0453,tp0453-tp0326 fusion protein, and use in syphilis diagnosis |
| abstract |
The present application provides methods of producing soluble Treponema pallidum protein Tp0453 (such as the fragment shown in SEQ ID NO: 3). For example, the protein can be expressed from the pET28a vector in a cell and the resulting soluble Tp0453 protein isolated from the cell. Also provided are the isolated soluble Tp0453 protein, as well as Tp0453-Tp0326 chimeric proteins ( e.g ., SEQ ID NO: 11), and methods of using the proteins to detect antibodies specific for T. pallidum subsp. pallidum , for example to diagnose syphilis. Devices and kits that incorporate Tp0453 protein and Tp0453-Tp0326 chimeric proteins, such as lateral flow devices, are also disclosed. Kits that include the soluble Tp0453 protein and kits that include solid substrates containing the soluble Tp0453 protein are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015276739-A1 |
| priorityDate |
2011-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |