| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd22425a37578d26f01800ae02665e10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71ff2ba629c25ea75b6ef21dd4554308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4003e6fc944efc04c4ccbe8181736d3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c85de9c9070d5064c5b5a3a9a71e34b9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate |
2012-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b482a1b867796e2cb2d788452cc58412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_948ffa372bfd85002d3f3a856f07545a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae3ea0f6c16be7db7ef177346bf679f7 |
| publicationDate |
2013-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2013004370-A1 |
| titleOfInvention |
Continuous flow production of gelatin nanoparticles |
| abstract |
The present invention relates to a continuous process for the preparation of gelatin based nanoparticles in a reactor comprising a process channel comprising a mixing element therein, the process comprising the following steps: A) feeding separately an aqueous gelatin solution at a first rate and a water-miscible organic solvent at a second rate to the process channel of the reactor to be mixed therein, to form a suspension of non-crosslinked gelatin based nanoparticles and B) crosslinking the non-crosslinked gelatin based nanoparticles, wherein the sum of the first rate and the second rate is chosen such that the reactor has a mixing efficiency as determined by the Villermaux/Dushman method of between 0.1 and 1.5 and the period from the time point at which the aqueous gelatin solution is fed to the reactor to the time point at which the mixture of the aqueous gelatin solution and the organic solvent contacts the mixing element is at most 15 seconds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015053629-A1 |
| priorityDate |
2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |