| abstract |
Disclosed are a method for the preparation of 3-butoxy-2-pyrazineformamide and use thereof, specifically the use of 3-butoxy-2-pyrazineformamide, pharmaceutically acceptable salts, hydrates or solvates thereof in the preparation of anti-virus drugs. By transforming into T1105 in vivo, 3-butoxy-2-pyrazineformamide shows anti-virus activity, evidently improves oral bioavailability of T1105 and extends the duration of action of T1105 in vivo. |