abstract |
Disclosed are microfluidic devices and kits for containing radioisotopes. The devices and kits comprises at least one confining geometry having a cross-section dimension below the beta(+) or beta(-) range of a radioisotope, when containing the radioisotope configured in such a way that neighboring segments of the confining geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the segments when containing the radioisotope. Methods of storage and synthesis of radiopharmaceuticals are also disclosed. In another aspect, the present invention relates to methods of storing radiotracers and synthesizing radiopharmaceuticals, using the aforementioned device. The radiotracers and radiopharmaceuticals comprises 18 F, 11 C, 14 C, 99m Tc, 123 I, 125 I, 131 I, 68 Ga, 67 Ga, 15 O, 13 N, 82R b, 62 Cu, 32 P, 89 Sr, 153 Sm, 186 Re, 201 Tl, 111 In, or combinations thereof. |